Cidofovir is a potent antiviral medication that
is typically used for the treatment of cytomegalovirus
(CMV) retinitis in AIDS patients. Its mechanism of
action involves the inhibition of DNA polymerase
activity. What this means is that it interferes with
the production of new cells and other necessary elements
for the survival of many viruses. In addition to its
benefits for CMV, cidofovir demonstrated efficacy agains
poxviruses, the family to which molluscum contagiosum
Cidofovir is typically an injectible medication but its
active drug can by formulated into a topical gel.
Case studies of the use of this topical preparation have shown
to be extremely successful at treating molluscum, primarily
being used in difficult cases involving immunosuppressed
patients (mostly with AIDS)1-2.
The cost of cidofovir is extremely high and this is
typically used as a last resort in cases that are unresponsive
to more conventional therapy.
1Antiviral Res. 2002
2Rev Med Virol. 2004
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